#BeatCancerEarly

90% of people survive if cancer is detected at Stage I.

5% survive if cancer is detected at Stage IV.1

How do we fight cancer?

Detecting cancer early is the key to defeating it, but today’s diagnostics are inconvenient, expensive, and poor predictors of early-stage cancer.

At Helio, our work is focused on finding cancer early when treatment options are available and the chances of beating cancer are highest—all from a simple blood draw.

Helio is revolutionizing cancer detection.

Helio is a leader in AI-driven, blood-based tests that accurately detect cancer early.

We are developing customer-friendly and cost-effective tests for liver, colon, breast, lung, and many other cancers.

ABOUT US

Helio is an AI-driven healthcare company focused on commercializing early cancer detection tests from a simple blood draw. For over 10 years, Helio has used AI on over 100,000 samples to identify cfDNA methylation patterns that detect cancer early. Helio is currently in clinical trials in the US and China with its leading product to detect liver cancer. Its pipeline includes colon, breast, and lung cancer, as well as 20 other cancers.

Helio is headquartered in Irvine, CA with facilities in West Lafayette, IN; Guangzhou (China); and Beijing (China).

Management Team

Our leadership team includes passionate, experienced experts with diverse industry backgrounds who are devoted to making a difference in patient lives.

Kenneth Chahine, Ph.D., J.D.

Chief Executive Officer

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  • As Executive Vice President and General Manager of Ancestry.com, a 1.6 billion dollar technology company, Ken led the launch of AncestryDNA, a large-scale e-commerce genetic genealogy test with revenues of > $500M. In 2019, Ken led the launch AncestryHealth, an e-commerce LDT genetic health product on a next-generation sequencing (NGS) platform.
  • Prior to Ancestry, he was the President and Chief Executive Officer at Avigen, a biopharmaceutical company that develops drugs for chronic neurological disorders, where he led the company in its mission to acquire, develop and commercialize innovative gene therapeutics.
  • Dr. Chahine is a patent attorney and on the faculty at the University of Utah’s College of Law currently teaching new venture development, intellectual property and licensing.
  • He earned a Ph.D. in Biochemistry from the University of Michigan, a J.D. from the University of Utah College of Law, and a B.A. in Chemistry from Florida State University.

Aarif Nakahooda

Chief Financial Officer

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  • Most recently, Mr. Nakhooda led the launch of Amazon retail in Singapore where he was CFO of the business, as well as a member of Amazon Asia Pacific’s Board of Directors. He spent 7 years at Amazon in several leadership roles, including head of finance for Amazon worldwide transportation and worldwide Prime reporting to the CFO. Prior to that, Mr. Nakhooda held leadership and strategy roles at EY and at various PE portfolio companies.
    • CFO of Amazon Singapore Retail where he had full P&L responsibility and built a local team that owned product development, selection, pricing and customer experience.
    • VP of Strategy and B2C Operations at Naspers – Founded in 1915, Naspers is a global internet group and one of the largest technology investors in the world. Reporting to group CEO responsible for B2C portfolio strategy and operating performance. Lead portfolio executives on critical business initiatives and funding strategies.
    • Head of Finance Worldwide Amazon Prime reporting to the Amazon CFO – Responsible for global program pricing and profitability, marketing, customer insights, Prime benefits and Prime delivery programs.
    • Finance Director – WW Transportation Finance leader for Amazon’s global investment strategy for Amazon owned and operated transportation capabilities.
    • Ernst and Young – Senior strategic role advising Fortune 500 companies on M&A opportunities, with a focus on buy vs. build analysis, due diligence, synergy analysis, and oversight of global carve-out activities.
    • University of British Columbia Applied Sciences, Electrical Engineer and MBA from the University of Chicago’s Booth School of Business.

Ben Oyler

Ben Oyler

Chief Operating Officer

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  • As Vice President of Strategy and Business Operations, Ben led the 2019 launch of AncestryHealth’s product offerings, an e-commerce LDT genetic health product on a next-generation sequencing (NGS) platform.
  • As a leader in the Operations of Ancestry’s DNA business Ben directed the operational and supply chain launch of the AncestryDNA product, a large-scale e-commerce genetic genealogy test with revenues of > $500M.
  • Ben has commercialized some of the world’s largests labs, manufacturing facilities and biorepositories with the scale to produce and run >10M samples per year and store tens of millions of samples.
  • Ben led the development of integrated and regulated technology and backend systems (CLIA, GMP, QMS, IOS9001/13485, GDPR, etc.) with focus on quality, customer privacy and security.
  • Prior to Ancestry Ben was responsible for several product launches including building operations, fulfillment and manufacturing capabilities in the US and Asia for multiple companies.
  • He earned an MBA at BYU Marriott School of Business, and a B.S. from Utah State University.

Richard Van Etten, MD, PhD

Chief Medical Advisor

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Dr. Van Etten is Chief Medical Officer for Laboratory for Advanced Medicine. Dr. Van Etten is also the Director of the Chao Family Comprehensive Cancer Center at UCI.He was previously the Director of the Tufts Cancer Center and Chief of the Tufts Hematology and Oncology Division.

Dr. Van Etten is the recipient of the Zucker Family Research Prize and the Lucille P. Markey Scholar Award. He is also a Carl and Margaret Walter Scholar and has published over 90 published peer reviewed papers.

He is a member of the American Association for Advancement of Sciences, American Society of Hematology, American Society of Clinical Oncology and the Eastern Cooperative Oncology Group. He is a contributing Editor to UpToDate, and on the editorial board of the Journal of Clinical Oncology.

Dr. Van Etten has board certifications in Hematology and Internal Medicine, is accredited by the American Board of Internal Medicine and is affiliated with the Long Beach Memorial Medical Center, Saddleback Memorial Medical Center and UC Irvine Medical Center.

Dr. Van Etten received his PhD in Biophysics and his MD from Stanford University and his BS in Biology and Mathematics from MIT.

Jinjie Hu, PhD

Chief Regulatory Officer

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Dr. Hu is currently the Chief Regulatory Officer for Laboratory for Advanced Medicine. Previously, she was the Lead Review Committee Chair and Senior Regulatory Scientist for In Vitro Diagnostics at the United States Food & Drug Administration (FDA). Dr. Hu was a CBER expert reviewer for applications of IVD devices detecting multiple analytes, and the principle reviewer for the scientific and regulatory review of CMC, pre-clinical and clinical sections for IVD device applications. She has collaborated with CDRH and CDER for reviewing companion diagnostic and combination devices, and Clinical Laboratory Improvement Amendments (CLIA) waiver application reviews.

Dr. Hu has completed the review of manufacturing facilities and processes. She has completed pre-license/pre-approval for manufacturing facility inspections at US and international companies, as well as cGMP post-approval manufacturing quality inspections. Additionally, she served as the FDA IVD expert in WHO Technical Working Group and Product Dossier Assessment for Prequalification of Diagnostics. She also served as Quality Assurance Manager to monitor the review progression of all applications submitted to OBRR products under MUDUFA dateline and to establish standard procedures for managed review processes.

Dr. Hu was a Senior Consultant at Biologics Consulting, and the former Chair of the International Network Committee of FDA Alumni.

She continues to be a World Health Organization (WHO) advisor for the Diagnostic Prequalification Program and has been a speaker for WHO training and workshops.

Dr. Hu received her PhD in Comparative Pathology at the University of California, Davis. She was a postdoctoral Fellow at the NIAID, NIH, Laboratory of Molecular Microbiology.

Board of Directors

Shu Li, PhD

Chairman of the Board

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  • Member of the Committee of 100
  • Founder & Chairman of WA Health Centers
  • Founder & Chairman of Cellular BioMedicine Group (NASDAQ: CBMG)
  • President & CEO of Jazz Semiconductor (NASDAQ: JAZ)
  • SVP of Conexant Systems (NASDAQ: CNXT)
  • Vice President of AlliedSignal/Honeywell (NYSE: HON)

Ken Chahine, PhD, JD

Chief Executive Officer

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  • Executive Vice President and General Manager of Ancestry.com
  • President & CEO, Avigen
  • Professor, University of Utah College of Law
  • PhD, Biological Chemistry, University of Michigan
  • JD, University of Utah College of Law

Terry Belmont

Chair of Nomination & Compensation Committee

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  • Chairman of Cellular Biomedicine Group
  • CEO and Vice Chancellor for Medical Center UCI
  • CEO of Long Beach Memorial Medical Center
  • CEO of President Kaiser Permanente SCA

Nadir Patel

Nadir Patel,  MBA

Chair of Finance & Audit Committee

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  • Independent director serving in private capacity with extensive international experience
  • Worked and studied in multiple countries abroad in North America, Europe and nearly a decade in Asia-Pacific
  • Former Chief Financial Officer with responsibilities of strategic planning, corporate finance, risk management and performance
  • Extensive knowledge of corporate governance and compliance practices through past participation on public sector Boards
  • MBAs from New York University’s Stern School of Business, the London School of Economics and Political Science, and the HEC Paris School of Management

Lebin Wu, MD

EMBA

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  • Chairman, Chinese Academy of Sciences Holdings ($100B assets under management)
  • Founding Director, Xinova
  • Co-Chair, International Capital Conference
  • Chairman, Pan-Pacific Energy Corp
  • Director of the Board, Legend Holding
  • Chairman & President, BioSino  Bio Technology & Sciences
  • Vice President, Institute of Biophysics, Chinese Academy of Sciences
  • Member, China Entrepreneur Club

Christopher De Rosa, MBA

Board Member

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  • President, US Commercial, Cigna HealthCare
  • Chairman, Social Wellth
  • President, Western Region, Cigna HealthCare
  • President, Southern California, Cigna HealthCare

Advisory Board

Salvador B. Sarabosing Jr., CISA, CRISC, MBA

Partner and Head of Risk Advisory, Blythe Global Advisors

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  • Former Senior Manager, Ernst & Young
  • Former Senior Manager, Grant Thornton LLP
  • Former Senior Director, Ingram Micro, Inc.
  • MBA University of Southern California

Richard Van Etten, MD, PhD

Director of UCI Cancer Center

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  • Former Director of Tufts Cancer Center
  • Zucker Family Research Price and the Lucille P. Markey Scholar Award
  • Carl and Margaret Walter Scholar
  • Over 90 published peer reviewed papers
  • PhD and MD from Stanford

Hans Keirstead, PhD

CEO, AIVITA Biomedical

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  • Founder and Director of Sue and Bill Gross Stem Cell Research Center
  • Former CEO, Ability Biomedical (sold to Bristol Myers Squibb)
  • Former CSO, Caladrius
  • Former CEO, California Stem Cell

Terry Belmont

Chairman of Cellular Biomedicine Group (NASDAQ: CBMG)

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  • Verity Health Systems Board of Directors
  • Former CEO, UCI Health
  • CEO of other major health care organizations, including executive leadership in Kaiser Permanente

Edward Nelson, MD

Chief, Division of Hematology/Oncology School of Medicine

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  • Associate Professor of Medicine
  • Associate Professor Molecular Biology & Biochemistry
  • University of California Irvine

FDA Hepatology Medical Advisors

Steven-Huy B. Han, MD

UCLA Jonsson Comprehensive Cancer Center

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  • Director, Hepatology Clinical Research Center, UCLA
  • Principle Investigator of NIH Hepatitis B Clinical Research Network
  • Editorial boards of Gastroenterology, Hepatology, etc
  • President of the Southern California Society of Gastroenterology

Ghassan K. Abou-Alfa, MD, MBA

Memorial Sloan-Kettering Cancer Center

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  • Oncologist, Memorial Sloan-Kettering Cancer Center
  • Professor of Medicine, Cornell University
  • Chair of the NCI Task Force for Hepatobiliary Cancers
  • President-Elect for the International Society of Gastrointestinal Oncology

Mindie H. Nguyen, MD, MAS, FAASLD

Stanford Cancer Institute

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  • Professor of Medicine and Director for the Hepatology Fellowship, Stanford University
  • Chair for the AASLD Hepatitis B Special Interest Group
  • Editorial Board of Gastroenterology, Hepatology, Lancet etc.

Robert Gish, MD

The Hepatitis B Foundation

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  • President of the Hepatitis B Foundation
  • Medical Director of The Hepatitis B Foundation
  • Faculty University of Nevada Reno and Las Vegas

Yujin Hoshida, MD, PhD

Liver Tumor Transitional Research Program, University of Texas Southwestern Medical Center

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  • Director, Liver Tumor Transitional Research Program, University of Texas Southwestern Medical Center
  • Member, AASLD Hepatobiliary Neoplasia SIG, Global Outreach Sub-committee

COLLABORATORS & PARTNERS

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¹Cancer Research UK. Survival three times higher when cancer is diagnosed  early. 2015 Aug 10.

The 10-year survival rate is more than 90% for those diagnosed at stage I cancer, compared with just 5% for those diagnosed at stage IV. The cancers included were bladder, bowel, breast, cervical, womb, malignant melanoma, ovarian, and testicular cancers—which together account for more than 40% of all cancer cases in the UK.